Poster: Construction of structurally defined heparan sulfate and chondroitin sulfate microarrays

A glycan microarray is a high-throughput tool for investigating the binding between glycans – polysaccharides or carbohydrates, such as heparan sulfate (HS) and chondroitin sulfate (CS) – and glycan-binding proteins (GBPs). As essential signaling molecules, glycans play key roles in a wide range of biological processes. HS is ubiquitous in extracellular matrix and basement membranes and influences immunological processes, cell adhesion and migration, inflammation, viral and bacterial infections, and cancer. CS differs from HS in one of the two repeating units and influences cancer metastasis, parasitic infections and neuron growth inhibition after injury. Download this poster to learn more about...