Tailoring LC-MS platforms for specific applications in drug design and detection

Liquid chromatography coupled with mass spectrometry is a popular analytical tool as liquid chromatography separates different substances present in a liquid sample, which can then be identified using mass spectrometry. Here, we discuss two recent developments in liquid chromatography–mass spectrometry (LC–MS) that enhance the technique for specific applications.  Automated diagnostic tool for drug detection Researchers have created an automated analytical tool to monitor antidepressants in patients to reduce the risk of side effects. [1, 2]  Liquid chromatography–tandem mass spectrometry (LC–MS/MS) has proven to be an accurate technique to identify and monitor therapeutic drugs in patients with high specificity. However, due...