Three advances in stem-cell-derived cardiac models and therapies

Aisha Al-Janabi, our Assistant Editor, explores recent cardiovascular disease research, including developing heart organoids with vascular cells, launching cardiac chips to the International Space Station (ISS) and using stem-cell therapy to repair damaged heart muscle. Introducing vascular cells into cardiac organoids Launching cardiac tissue chips into space Engineered stem cells repair damaged heart muscle Introducing vascular cells into cardiac organoids Organoids are 3D cellular complexes generated from human-derived adult stem cells that self-organize into tissue models with high parity to their in vivo counterparts due to the developmental biological signals provided by their environment. These models provide an accurate platform...