Anti-idiotype antibodies: a powerful weapon for PK/ADA assays

Written by Sino Biological

Assessing the safety and efficacy of biotherapeutics is imperative during the drug development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars. For PK/ADA assays, anti-idiotype antibodies (anti-IDs) are powerful tools to measure the concentration of antibody drugs in patient samples and serve as positive controls for anti-drug antibodies (ADA). Download this Application Note by Sino Biological to learn more about: The applications of anti-IDs in PK/ADA assays Sino Biological’s anti-idiotype antibody generation packages Case Study #1: development of anti-IDs targeting bispecific antibodies (BsAbs) Case Study #2: generation...

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