Cancer cachexia: a vital field finally gets its due
Teresa Zimmers (left) runs a laboratory at the Oregon Health and Science University (OR, USA) focused on the study of cachexia, the systemic muscle wasting syndrome caused by tumors, for which there are no approved effective therapies. Here, she discusses the sophisticated animal models that she uses to seek out the molecular, cellular and physiologic mechanisms that cause cachexia to target them as potential therapy options. How much do we currently understand about how tumors cause cachexia? As a field, cancer cachexia is much less well developed than the field of cancer in general. For a long time, there was...
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