eBook | Cytokines in immunotherapy

Written by Annie Coulson (Digital Editor)

Cytokines are a diverse group of small proteins produced and released by various cells. These molecules play a crucial role in regulating the immune system, communicating with it to modulate the body’s response to infection and disease, including cancer. Cytokines and their receptors can therefore be utilized in immunotherapy, serving as messengers to stimulate or suppress immune responses. However, challenges such as their short lifespan in vivo, severe toxicity and limited efficacy hinder the widespread clinical use of cytokines.

In this eBook, we explore the use of cytokines in immunotherapy and how their modulation and implementation can be used to optimize new and existing therapeutic approaches.

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  • Introduction
  • In Focus summary: Cytokines in immunotherapy
  • Infographic: Next-generation cytokines for cancer
  • White Paper: Advancing immunotherapy development with high-quality cytokines
  • Editorial: Taming the beast: engineering strategies and biomedical potential of antibody-based cytokine mimetics
  • White Paper: Next-generation cytokines for immunotherapy: a new frontier in oncology
  • Special report: Interleukin-18 in cancer immunology and immunotherapy
  • Review: Advances in engineering and delivery strategies for cytokine immunotherapy

This content was supported by Sino Biological.