Microbial trojan horses: disrupting the tumor microenvironment

Pedro Correa de Sampaio (left) is the CEO and Co-Founder of Neobe (Stevenage, UK), a company engineering microbial trojan horses to carry payloads into solid tumors, which can break down fibrotic barriers in the tumor microenvironment. This approach aims to enable greater drug penetration and immune cell activity within solid tumors, increasing the curative potential of existing therapeutics. At ELRIG Drug Discovery 2024 (2–3 October 2024; London, UK), Digital Editor Beatrice Bowlby caught up with Pedro to learn more about targeting solid tumors and the potential of Neobe’s synthetic biology platform in developing effective tools for making solid tumors more...