eBook: Non-viral vectors: lipid nanoparticles
Lipid nanoparticles are the most clinically advanced non-viral gene delivery system. Their ability to encapsulate and protect fragile nucleic acids, such as DNA, mRNA, and siRNA, while facilitating their efficient delivery into cells makes them a promising platform for gene delivery.
In this eBook, produced in collaboration with Precision NanoSystems (Vancouver, Canada), we’ll explore several pivotal applications of lipid nanoparticles. These include their role in mRNA-based vaccines, like those developed for COVID-19, and their utilization in the targeted delivery of siRNA molecules to address conditions like cancer.
We’ll also explore how lipid nanoparticles are advancing the field of cell therapy in our interview with Sadik Kassim, Chief Technology Officer of Genomic Medicines at Danaher Corporation (DC, USA).
- FOREWORD Welcome to our eBook on non-viral vectors
- INTERVIEW Advancing cell therapy with lipid nanoparticles: an interview with Sadik Kassim
- EDITORIAL How has nanomedical innovation contributed to the COVID-19 vaccine development?
- ARTICLE Genomic medicine drug discovery and screening, a digital era for RNA-LNP therapeutics
- REVIEW Nanoparticle-siRNA: a potential strategy for ovarian cancer therapy?
- ARTICLE Genome editing using mRNA-lipid nanoparticles for CAR-T cell therapy
- SPECIAL REPORT Nanotherapeutic systems for delivering cancer vaccines: recent advances
- ARTICLE Accelerating the development and scale-up of mRNA vaccines
This eBook was supported by Precision NanoSystems
