How is the integration of CRISPR and 3D culture systems advancing disease modeling and personalized medicine? – Find out in your latest issue of BioTechniques!

In this issue of BioTechniques, we present a colorimetric-based method for quantifying biotin binding capacity, the development of a portable device for RNA extraction and a protocol for assessing cell-line immortality.

Technology News

CRISPR in 3D: innovations in disease modeling and personalized medicine

Editorial

Importance of a reference ladder in analytical testing of CRISPR HDR donor ssDNA templates

Reports

A HABA dye-based colorimetric assay to detect unoccupied biotin binding sites in an avidin-containing fusion protein

A single-cell 3D dynamic volume control system for chondrocytes

Development and validation of a portable device for lab-free versatile nucleic acid extraction

Benchmark

Optimized for routine: highly sensitive fluorescent Telomeric Repeat Amplification Protocol (f-TRAP)

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