Metabolic rate monitoring of undifferentiated iPS cells and expression analysis of differentiation markers

One method for quantitative evaluation of the state of cells is to track cell metabolism through analysis of the culture medium; however, it’s not possible to gain an accurate understanding of the state of cells by sampling several times a day. Though there are evaluation methods using automated sampling, this is difficult for cultures in multi-well plates that are used in laboratories.

Therefore, PHCbi developed LiCellMo™, a live cell metabolic analyzer, which can continuously measure glucose and lactate concentrations in the culture medium in common, commercially-available, 24-well plates through in-line monitoring. This allows changes in cell state over time to be quantified.

LiCellMo is available for purchase in the U.S., Canada, and select other geographies globally. For research and education use only, not for use in diagnostic procedures in the U.S. or Canada. This product has not been approved or cleared as a medical device by the U.S. Food and Drug Administration or Health Canada. 

This feature was supported by PHC Corporation of North America.