Modeling a heart attack: researchers develop human cardiac organoids

Researchers have developed human cardiac organoids in order to model myocardial infarction and drug cardiotoxicity. A team of biomedical researchers from the Medical University of South Carolina and Clemson University (both SC, USA) have succeeded in developing human cardiac organoids, less than 1mm in diameter, that can replicate the physiological conditions that occur during a heart attack. "We were essentially able to take that 3D complex nature of a heart attack and then downsize it into a microtissue model," remarked Dylan Richards (Clemson University), a co-author on the study which was published recently in Nature Biomedical Engineering. In the USA,...