Heparan sulfate antibodies accelerate glycobiology research
Working with leading research institutions, AMSBIO (Oxford, UK) has established itself as a premier supplier of high quality heparan sulfate (HS) monoclonal antibodies, which are driving breakthroughs in glycobiology research.
HS is widely distributed on cell surfaces and basement membranes in mammals. It participates in important biological processes, interacting with many biologically active proteins. However, due to its non-immunogenic nature, developing effective antibodies against HS has long been a challenge.
AMSBIO has overcome these limitations by offering a range of hybridoma-derived anti-HS antibodies, such as 10E4, 3G10 and JM403. The popularity of their HS antibodies is because of the HS antibodies’ high sensitivity, specificity and affinity for target antigens; additionally, they work across many model species. All HS antibodies supplied by AMSBIO are rigorously validated to accurately detect and quantify cell surface HS, ensuring reliable data for diverse applications, from investigating viral infections to exploring cancer and immunological disorders. When preserved using CELLBANKER® cryopreservation media, cell surface HS integrity is maintained, ensuring reliable and reproducible results in downstream assays.
To provide an informed background on the importance of glycobiology, AMSBIO has worked with Doug Dyer, an immunology researcher at the University of Manchester (UK) to create an original blog. In this blog, Dyer discusses and illustrates with research citations how glycobiology is increasingly being recognized as the ‘dark matter’ of biology, with new research revealing that incorporating glycans into our understanding is redefining fundamental biological processes. At the forefront of these advances, AMSBIO has established itself as a premier supplier of high-quality tools, including their flagship HS monoclonal antibodies.
For further information on heparan sulfate antibodies, please visit here or contact them directly.
AMSBIO has in-depth expertise in extracellular matrices (ECMs) to provide elegant solutions for studying cell motility, migration, invasion and proliferation. This expertise in cell culture and the ECM allows AMSBIO to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics.
For drug discovery research, AMSBIO offers assays, recombinant proteins and cell lines. Drawing upon a huge and comprehensive biorepository, AMSBIO is widely recognized as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical-grade products for stem cells and cell therapy applications. This includes GMP cryopreservation technology and high-quality solutions for viral delivery.