Application Note: Protein A HPLC vs. protein A biolayer interferometry for monoclonal antibody quantitation

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing. This Application Note assesses the relative merits of protein A high-pressure liquid chromatography (HPLC) and protein A biolayer interferometry using the Sartorius Octet® R8 system to determine MAb concentration in a complex feedstock.