Epitope binning

Therapeutic monoclonal antibody development is growing significantly in the biopharmaceutical industry. However, for monoclonal antibodies to play a beneficial role in developing new vaccines and diagnostic tools, it is essential that selected antibodies possess specific characteristics. To consider binding affinity and binding specificity, researchers often use a technique called epitope binning.

But, what is epitope binning? Why is it an important step in developing therapeutic monoclonal antibodies? And how can you conduct it?

We answer these questions and more in our In Focus with Sartorius (Göttingen, Germany), which presents an introductory video, informative infographic and podcast with an expert.