DNA and mRNA transfection in the modern lab

If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in your time. However, this technique comes in many forms and can deliver a wide variety of payloads into your target cells, each with slightly different quirks and preferences.

In this In Focus, we give a whistle-stop tour of the different transfection methods before descending into the details of DNA vs mRNA-based transfection, providing key tips for the selection of your transfection method and materials.