Showcasing biotech: the tools facilitating breakthroughs in sequencing, imaging and data management
At this year’s ABRF Annual Meeting (23–26 March; NV, USA), biotech companies had the opportunity to showcase their technology, highlighting how their products are facilitating breakthroughs in the fields of sequencing, imaging and data management.
10x Genomics: single-cell and spatial approaches for uncovering mechanisms of lung disease
The meeting kicked off on Monday, 24 March, with a breakfast session where Walter Eckalbar, Genomics CoLab Director at the University of California San Francisco (CA, USA) discussed how he’s using 10x Genomics’ (CA, USA) Chromium, Visium and Xenium platforms to study lung disease. 10x Genomics representatives in the session then highlighted how 10x has made pairing GEM-X microfluidics and robust single-cell profiling more cost-effective and accessible, before showcasing Visium HD’s spatial discovery power, which offers single-cell-scale resolution with continuous tissue coverage. Finally, they focused on the Xenium Prime 5K, which can characterize up to 5000 genes in cells and tissues through ultra-precise single-cell spatial imaging.
Learn more about 10x Genomics’ single-cell and spatial technologies >>>
Glencoe Software: expanding the OMERO Plus ecosystem for image data management
Glencoe Software’s (WA, USA) OMERO Plus is a cornerstone technology for image data management. OMERO Plus is a database – with a data management interface – that allows researchers to view, manage, share, analyze, mine and publish data from scientific images and associated comments, results and documents. At ABRF, Glencoe Software’s Head of Applications, Emil Rozbicki, and Head of Product, Erin Diel, announced new ways to work with OMERO Plus, demonstrating how one system can enable a whole suite of data management tools for spatial biology, high-content screening and digital pathology.
Learn more about Glencoe Software’s data management technology >>>
What’s new in biotech? Read about the products and partnerships that are optimizing qPCR workflows, advancing spatial biology research and creating sustainable cell cultivation processes. Additionally, catch up on recent company news and funding outcomes.
Miltenyi Biotec: introducing light sheet microscopy at the Yale West Campus Imaging Core
The Yale West Campus Imaging Core (CT, USA) was launched in 2014 with the aim of providing a shared microscopy resource to support the university’s research. Adding to their fleet of microscopy technologies, the Imaging Core has partnered with Miltenyi Biotec (Bergisch Gladbach, Germany) to integrate its UltraMicroscope Blaze light sheet microscope into their facility. However, this integration brings with it both challenges and opportunities. In this session at ABRF, Imaging Core representatives shared their insights into how they successfully support users through the stages of sample preparation, data acquisition and image analysis. Additionally, they highlighted the specific benefits this advanced technology brings to their research community and how it has enhanced the capabilities of their core facility.
Learn more about Miltenyi Biotec’s light sheet microscope >>>
Roche: sequencing by expansion, a versatile sequencing technology
This presentation provided an insight into Roche’s (Basel, Switzerland) novel next-generation sequencing technology, sequencing by expansion (SBX). SBX encodes the sequence of a target nucleic acid molecule into a surrogate polymer called Xpandomer, which is then threaded through a porous sensor module for parallel sequencing at rates of hundreds of millions of bases per second. SBX offers flexible read lengths and operations, allowing for tunable sample needs and a broad range of applications. Engineered for efficiency, it delivers high accuracy in detecting single nucleotide variants and insertions/deletions.
Learn more about Roche’s SBX technology | Press release >>>
PacBio: accessible HiFi sequencing with Vega and Revio
PacBio (CA, USA) dedicated their ABRF technology showcase to their new benchtop HiFi sequencing system, Vega, in addition to an SPRQ chemistry update to their Revio system that enables a 4-fold reduction in genomic DNA input and a 33% increase in HiFi yield. The presentation went further to discuss their soon-to-be-released Ampli-Fi protocol and how it will enable new sample types and applications on Revio and Vega.
