Controlling gene expression with synthetic transcription factors

Lacra Bintu is an Assistant Professor of Bioengineering at Stanford University (CA, USA) who leads an interdisciplinary research group with a focus on developing new tools for mammalian synthetic biology for gene and chromatin control. At the European Laboratory Research and Innovation Group’s (ELRIG) Research and Innovation conference (29–30 March 2023; Cambridgeshire, UK), Lacra presented a talk on developing compact gene control utilizing high-throughput measurements (the preprint of which has recently been deposited on bioRxiv). Our Assistant Editor, Aisha Al-Janabi, spoke with Lacra to learn more about synthetic transcription factors, measuring gene expression and epigenetic memory. Could you tell me...