Re-writing regulation

A new map of yeast-protein-binding locations has updated the traditional model of gene regulation. A new research effort has produced the most high-resolution map to-date of yeast chromosome architecture and gene regulation. More precise maps of the model organism could provide interesting new insights into higher organism biology. The study, carried out by researchers from Pennsylvania State University (PSU; PA, USA) and Cornell University (NY, USA), saw ChIP-exo/seq used to map the precise binding sites of over 400 Saccharomyces cerevisiae chromosomal proteins that interact with the genome – some at only a few locations, some at thousands. "When I first...