Can engineered nanoparticles treat wet age-related macular degeneration?

Researchers at Johns Hopkins University (MD, USA) described in Science Advances the development of a new nanoparticle-delivered gene therapy that could help treat wet age-related macular degeneration and potentially improve patient compliance as well as reduce strain on caregivers. Wet age-related macular degeneration is an inherited disease characterized by abnormal blood vessel growth that damages the light-sensitive tissue in the back of the eye. Currently, there are an estimated 1.6 million people in the USA suffering with wet age-related macular degeneration. Peter Campochiaro (Johns Hopkins University) commented: “Some of the most prevalent inherited retinal degenerations are due to mutations in...