Elastic RNA nanoarchitectures are effective at targeting tumors and quickly leaving the body

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James, Columbus, OH, USA) have published a study showing that the elastic properties of RNA nanoparticles makes them better at targeting tumors than similar nanoparticles made from gold or iron. The same rubbery properties led to less accumulation of the RNA nanoparticles in healthy organs. The study, published in ACS Nano, revealed that RNA architectures could be manipulated at will to form different shapes and could return to their original structure after being deformed. The researchers used...