Researchers use synthetic protein nanoparticles for glioblastoma therapy in mice

Published in Nature Communications, researchers from the University of Michigan (MI, USA) have described their engineering and use of synthetic protein nanoparticles to deliver molecules that may help promote tumor regression into the brains of mice with glioblastomas. Glioblastoma represents one of the most common and aggressive brain cancers forms seen in adults; the average 5-year survival rate for individuals diagnosed with glioblastoma is less than 5%. Clinical progress in the treatment of glioblastoma has been slow, in part due to a lack of effective drug delivery strategies. For example, whilst the transcription factor STAT3 has been implicated in multiple...