Scaling up a nanoimmunotherapy for atherosclerosis through preclinical testing

A working group involving researchers from many different institutions across North America and the Netherlands, including Icahn School of Medicine at Mount Sinai, (NY, USA), Memorial Sloan Kettering Cancer Center, (NY, USA), and University of Amsterdam (Netherlands), have been working on scaling up nanoimmunotherapies from murine models so that they are more translatable into human medicine.   Atherosclerosis is a chronic inflammatory disease affecting the arteries and is one of the underlying causes of 50% of deaths in the western world. It is defined by accumulation of low-density lipoproteins and causing inflammation in arteries and can lead to heart attacks, stroke...