Bacteria provide inspiration for novel therapeutic delivery approaches

“Delivery of therapeutic molecules is a major bottleneck for medicine, and we will need a deep bench of options to get these powerful new therapies into the right cells in the body,” commented Feng Zhang, an Associate Professor at MIT (MA, USA) who’s research group recently published a paper on a bacterial injection system. Our Assistant Editors, Beatrice Bowlby and Aisha Al-Janabi, covered two different research groups that have harnessed natural bacterial systems and their syringe-like machinery to deliver therapeutic payloads, one focusing on delivering antibodies to the gut and another on protein delivery to different cell types. Smart microbes:...