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PromethION: Flexible, large-scale, direct DNA and RNA sequencing

Written by Oxford Nanopore

The Oxford Nanopore PromethION devices enable high-output, high-throughput sequencing of native DNA or RNA samples on demand. PromethION 24 (P24) and PromethION 48 (P48), operating up to 24 or 48 flow cells respectively, are capable of delivering terabases of sequence data, with base modifications, in a flexible fashion with no batching necessary. Each flow cell can deliver up to 290 Gb* of data, enabling the lowest price per gigabase for nanopore sequencing in a flexible offering that can accommodate multiple users with wide and varying experimental demands. Invest with capital or consumable budget, with options to offer nanopore sequencing as a service.

Why PromethION?

  • Ultra-high throughput: stream up to 14 Tb of data** in real-time for immediate analysis
  • On-demand, flexible sequencing: run as few or as many flow cells as required
  • Powerful compute: augment local data handling capabilities
  • Population-scale sequencing: generate sub $1000 human genomes
  • No capital cost: pay just for consumables

Why nanopore sequencing technology?

Oxford Nanopore devices sequence DNA/RNA directly, which means the data is rich and can be streamed in real-time, to provide rapid insights. It’s possible to sequence short to ultra-long fragments of DNA for a truly comprehensive picture. The technology is fully scalable — from pocket to population scale.

With this new generation of high-performance nanopore-based sensing technology, Oxford Nanopore aim to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere.

Click here to get more information on the PromethION

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* Theoretical maximum output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

**Theoretical max for the P48 device

This content has been provided by Oxford Nanopore