Infographic: Primer extension target enrichment for NGS
Researchers often enrich genomic regions of interest prior to next-generation sequencing (NGS) to reduce costs, decipher the roles of individual genes in complex diseases or investigate rare and low-frequency genetic variants. There are various techniques for doing this, including amplicon-based methods, hybridization-based methods and primer extension target enrichment (PETE).
Download this infographic to explore to various methods available for enriching genomic regions of interest.
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Find out:
- An introduction to NGS target enrichment
- How target enrichment techniques compare in terms of time, workflow ease of use, coverage uniformity and variants detected
- The PETE workflow
Illustration by Hannah Morton.