Proteomics
The term ‘proteomics’ was first coined in 1994 by Marc Wilkens, who went on to establish the first dedicated proteomics laboratory in 1995. This first definition referred to the large-scale study of proteomes, the entire set of proteins present in a cell type, tissue or organism. The definition has now evolved into a more
inclusive definition and often includes other ‘omic’ technologies such as genomics and transcriptomics, all of which fall under the umbrella term ‘multiomics’. The goal of proteomics is to gain an integrated view of biological processes by studying all the proteins in a sample, rather than each one individually.
Proteomic technologies can be used to identify proteins, evaluate the total number of proteins, determine the structure, activity and interactions of proteins, and detect post-translational modifications, such as phosphorylation, which are critical to a protein’s function.
For more information and research papers about the techniques involved in proteomics visit the BioTechniques journal site.