Recent developments in protein engineering technologies, such as cell-free methods, have brought the field into a golden era of innovation, creating new opportunities and ingenious products that can be designed for a host of therapeutic, diagnostic or investigative applications. One group of products that have benefitted from these developments are recombinant proteins, in particular recombinant antibodies.

In this eBook, we discuss the advantages of recombinant antibody production over more traditional hybridoma-based technologies for the generation of monoclonal antibodies and the expression systems used to create them. Get an overview of the many formats of recombinant antibodies available and their applications. Dive deep into the use of E. coli and baculovirus-insect expression systems and the cell-free expression systems available for recombinant protein and antibody production.

With this interactive eBook, you can also hear from two experts on the evolution of recombinant proteins and antibodies, the most exciting developments in their production and some of the most interesting applications of these molecules in the research space.

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Contents:

• Introduction
• Interview: Ensuring quick, efficient CRO services for recombinant protein and antibody production
• App Note: Recombinant antibody formats, expressions, and applications
• Benchmark: High-yield expression of periplasmic single chain variable fragments by solid Escherichia coli cultures
• App Note: Recombinant protein expression using a baculovirus-insect cell system
• Review: Cell-free protein synthesis: advances on production process for biopharmaceuticals and immunobiological products
• Podcast: Producing challenging proteins in the golden age of protein engineering
• Podcast: The evolution of recombinant antibodies

This eBook was supported by Sino Biological.