Bioimaging and analysis

The goal of bioimaging has always been to capture the maximum amount of information about a biological process, with the minimum amount of interference. To achieve this goal there are two key aspects that need to be operating well: imaging instrumentation, to capture high-resolution images in a minimally invasive manner; and the image analysis methods, to extract as much information as possible. When working in tandem, these techniques can act as a powerful tool for therapeutic development and the advancement of personalized medicine.

However, the pursuit of more accurate models for disease and basic biology has led to more complex, 3D subjects for image capture and the need to capture processes real-time in live cells has driven the instrumentation to become more sophisticated. These systems are capable of delivering highly complex, detailed images that require cutting-edge analysis models to mine the maximum information from each biological sample being evaluated.

This spotlight will explore:

• Technological developments in bioimage instrumentation
• The role of AI in image analysis
• Top tips to produce robust, reproducible results and objective analyses in physiologically relevant conditions