An introduction to epitope binning

Epitope binning is an important step towards selecting the best monoclonal antibody for a specific therapeutic purpose as it allows researchers to narrow down the number of candidates by assessing binding affinity and binding specificity. Epitope binning is a competitive immunoassay that is used to characterize the binding of monoclonal antibodies to specific sites – epitopes – on a target antigen.

Animation by James Harvie.

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