An introduction to epitope binning

Written by Beatrice Bowlby (Digital Editor)
Drug discovery and development Lab design and machinery Molecular biology

Epitope binning is an important step towards selecting the best monoclonal antibody for a specific therapeutic purpose as it allows researchers to narrow down the number of candidates by assessing binding affinity and binding specificity. Epitope binning is a competitive immunoassay that is used to characterize the binding of monoclonal antibodies to specific sites – epitopes – on a target antigen.

Animation by James Harvie.

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