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Cytokines and receptors in cancer immunotherapy

Cytokines are a key area of interest in cancer immunotherapy. Interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21 comprise a cytokine family based on a shared receptor component, the common cytokine receptor γ chain (γc). γc family cytokines generally activate three major signaling pathways (PI3K-Akt, RAS-MAPK, and JAK-STAT) to regulate the development, survival, proliferation, differentiation, and function of cells in both the innate and adaptive immune systems.

Recently, designer cytokines for the γc family have shown significant therapeutic potential in cancer, allergy, immunodeficiency, and autoimmunity research. This webinar discusses the current landscape of cytokine-based cancer immunotherapy. It will primarily focus on the critical biological roles and therapeutic applications of γc family cytokines and receptors and will also look ahead to future developments within the field.

What will you learn?Who may this interest?Speaker

What will you learn?

  • General overview of cytokines
  • Introduction to γc family cytokines
  • Roles and applications of γc family cytokines in cancer immunotherapy
  • Future developments of γc family cytokines in cancer immunotherapy

Who may this interest?

  • Researchers studying cancer
  • Researchers studying immunotherapy
  • Pharmaceutical companies developing cancer drugs

Speaker

Sylvia Xie
Product Scientist
Sino Biological

Sylvia Xie is a Product Scientist at Sino Biological, a manufacturer of high-quality research reagents, where she manages the product catalog and supports product development.

Prior to joining Sino Biological, Sylvia received her MS degree from the University of Houston (TX, USA) in Biomedical Engineering, where her research focused on targeted drug therapy in autoimmune diseases.

This webinar was recorded on Thursday 25th August 2022

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